Improved Imputation of Common and Uncommon Single Nucleotide Polymorphisms (SNPs) with a New Reference Set
نویسندگان
چکیده
Zhaoming Wang 1,2 Kevin B. Jacobs 1,2 Meredith Yeager 1,2 Amy Hutchinson 1,2 Joshua Sampson 2 Nilanjan Chatterjee 2 Demetrius Albanes 2 Sonja I. Berndt 2 Charles C. Chung 2 W. Ryan Diver 3 Susan M. Gapstur 3 Lauren R. Teras 3 Christopher A. Haiman 4 Brian E. Henderson 4 Daniel Stram 4 Xiang Deng Ann W. Hsing 2 Jarmo Virtamo 5 Michael A. Eberle 6 Jennifer L. Stone 6 Mark P. Purdue 2 Phil Taylor 2 Margaret Tucker 2 Stephen J. Chanock 2
منابع مشابه
Single Nucleotide Polymorphisms and Association Studies: A Few Critical Points
Uncovering DNA sequence variations that correlate with phenotypic changes, e.g., diseases, is the aim of sequence variation studies. Common types sequence variations are Single nucleotide polymorphism (SNP, pronounced snip).SNPs are the third-generation molecular marker. SNP represents a DNA sequence variant of a single base pair with the minor allele occurring in more than 1% of a given popula...
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